SUGARSKETCHER: QUICK AND INTUITIVE ONLINE GLYCAN DRAWING

D. Alocci^a,b, Pavla Suchánková^c,d, R. Costa^e, N. Hory^e, J. Mariethoz^a,b, Radka Svobodová Vařeková^c,d, Ph. Toukach^f, F. Lisacek^a,b,g

^aProteome Informatics Group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland
^bComputer Science Department, University of Geneva, Switzerland
^cCEITEC–Central European Institute of Technology, Masaryk University Brno, Czech Republic ^dNational Centre for Biomolecular Research, Faculty of Science, Brno, Czech Republic ^ePolytech Nice Sophia, Campus SophiaTech, Sophia-Antipolis, France
^fZelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
^eSection of Biology, University of Geneva, Switzerland

KEYWORDS: carbohydrate; 2D structure; software; SNFG notation

MDPI Molecules, 2018, 23(12), ID. 3206

DOI: 10.3390/molecules23123206

SugarSketcher is an intuitive and fast JavaScript interface module for online drawing of glycan structures in the popular Symbol Nomenclature for Glycans (SNFG) notation and exporting them to various commonly used formats encoding carbohydrate sequences (e.g., GlycoCT) or quality images (e.g., svg). It does not require a backend server or any specific browser plugins and can be integrated in any web glycoinformatics project. SugarSketcher allows drawing glycans both for glycobiologists and non-expert users. The “quick mode” allows a newcomer to build up a glycan structure having only a limited knowledge in carbohydrate chemistry. The “normal mode” integrates advanced options which enable glycobiologists to tailor complex carbohydrate structures. The source code is freely available on GitHub and glycoinformaticians are encouraged to participate in the development process while users are invited to test a prototype available on the ExPASY web-site and send feedback.

Наука: CSDB

Дом : Наука