THREE-DIMENSIONAL STRUCTURES OF CARBOHYDRATES AND WHERE TO FIND THEM (review)
1 N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
2 Higher Chemical College, D. Mendeleev University of Chemical Technology of Russia, Moscow, Russia
KEYWORDS: carbohydrate, spatial structure, model build, database, web tool, glycoinformatics, structure validation, PDB glycans, structure visualization, molecular modeling
International Journal of Molecular Sciences, 2020, т.21(20), ID 7702 (стр. 1-46)
DOI: 10.3390/ijms21207702, PMID: 33081008
Analysis and systematization of accumulated data on carbohydrate structural diversity is a subject of great interest for structural glycobiology. Despite being a challenging task, development of computational methods for efficient treatment and management of spatial (3D) structural features of carbohydrates breaks new ground in modern glycoscience. This review is dedicated to approaches of chemo- and glyco-informatics towards 3D structural data generation, deposition and processing in regard to carbohydrates and their derivatives. Databases, molecular modeling and experimental data validation services, and structure visualization facilities developed for last five years are reviewed.
 Наука: CSDB |
 Дом : Наука |